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about the study Patient registries are critical to such studies – learn more and sign up Learn what you can do to manage cognitive problems… Watch an MS expert discuss how cognitive rehabilitation Learn proactive strategies that can preserve cognitive function “Large-scale online assessment uncovers a distinct Multiple Sclerosis subtype with selective cognitive impairment” by Annalaura Lerede, Alexandra Moura, Valentina Giunchiglia, Elisa Carta, William Trender, Katherine Tuite-Dalton, James Witts, Elaine Craig, Sarah Knowles, Jeff Rodgers, Eleonora Cocco, Peter J. Hellyer, Rod Middleton, Richard Nicholas & Adam Hampshire is published in Nature Communications (Volume 16, Article number: 6938 (2025))Among 19,188 people enrolled in the United Kingdom’s MS Registry, a subgroup of people who showed cognitive changes using an online assessment, did not show motor problems when evaluated with the 9-hole peg test (which measures hand function). Although cognitive problems affect as many as half of people with MS, these changes are not routinely assessed by physicians, and are not always evaluated in clinical trials of experimental medications. This study shows that online, at-home assessment of these problems is feasible, and might be especially important in identifying disease activity that is not showing up in a physical examination. Read more about the study Patient registries are critical to such studies – learn more and sign up Learn what you can do to manage cognitive problems… Watch an MS expert discuss how cognitive rehabilitation Learn proactive strategies that can preserve cognitive function “Large-scale online assessment uncovers a distinct Multiple Sclerosis subtype with selective cognitive impairment” by Annalaura Lerede, Alexandra Moura, Valentina Giunchiglia, Elisa Carta, William Trender, Katherine Tuite-Dalton, James Witts, Elaine Craig, Sarah Knowles, Jeff Rodgers, Eleonora Cocco, Peter J. Hellyer, Rod Middleton, Richard Nicholas & Adam Hampshire is published in Nature Communications (Volume 16, Article number: 6938 (2025))about the study Patient registries are critical to such studies – learn more and sign up Learn what you can do to manage cognitive problems… Watch an MS expert discuss how cognitive rehabilitation Learn proactive strategies that can preserve cognitive function “Large-scale online assessment uncovers a distinct Multiple Sclerosis subtype with selective cognitive impairment” by Annalaura Lerede, Alexandra Moura, Valentina Giunchiglia, Elisa Carta, William Trender, Katherine Tuite-Dalton, James Witts, Elaine Craig, Sarah Knowles, Jeff Rodgers, Eleonora Cocco, Peter J. Hellyer, Rod Middleton, Richard Nicholas & Adam Hampshire is published in Nature Communications (Volume 16, Article number: 6938 (2025))Among 19,188 people enrolled in the United Kingdom’s MS Registry, a subgroup of people who showed cognitive changes using an online assessment, did not show motor problems when evaluated with the 9-hole peg test (which measures hand function). Although cognitive problems affect as many as half of people with MS, these changes are not routinely assessed by physicians, and are not always evaluated in clinical trials of experimental medications. This study shows that online, at-home assessment of these problems is feasible, and might be especially important in identifying disease activity that is not showing up in a physical examination. Read more about the study Patient registries are critical to such studies – learn more and sign up Learn what you can do to manage cognitive problems… Watch an MS expert discuss how cognitive rehabilitation Learn proactive strategies that can preserve cognitive function “Large-scale online assessment uncovers a distinct Multiple Sclerosis subtype with selective cognitive impairment” by Annalaura Lerede, Alexandra Moura, Valentina Giunchiglia, Elisa Carta, William Trender, Katherine Tuite-Dalton, James Witts, Elaine Craig, Sarah Knowles, Jeff Rodgers, Eleonora Cocco, Peter J. Hellyer, Rod Middleton, Richard Nicholas & Adam Hampshire is published in Nature Communications (Volume 16, Article number: 6938 (2025))nationalmssociety.org, Facebook , X (formerly known as Twitter), Instagram , YouTube or 1-800-344-4867 . " c-nmssatomrichtext_nmssatomrichtext-host="">About Multiple Sclerosis Multiple sclerosis is an unpredictable disease of the central nervous system. Currently there is no cure. Symptoms vary from person to person and may include disabling fatigue, mobility challenges, cognitive changes, and vision issues. An estimated 1 million people live with MS in the United States. Early diagnosis and treatment are critical to minimize disability. Significant progress is being made to achieve a world free of MS. About the National Multiple Sclerosis Society The National MS Society, founded in 1946, is the global leader of a growing movement dedicated to creating a world free of MS. The Society funds cutting-edge research for a cure, drives change through advocacy and provides programs and services to help people affected by MS live their best lives. Connect to learn more and get involved: nationalmssociety.org , Facebook , X (formerly known as Twitter), Instagram , YouTube or 1-800-344-4867 . nationalmssociety.org, Facebook , X (formerly known as Twitter), Instagram , YouTube or 1-800-344-4867 . " c-nmssatomrichtext_nmssatomrichtext-host="">About Multiple Sclerosis Multiple sclerosis is an unpredictable disease of the central nervous system. Currently there is no cure. Symptoms vary from person to person and may include disabling fatigue, mobility challenges, cognitive changes, and vision issues. An estimated 1 million people live with MS in the United States. Early diagnosis and treatment are critical to minimize disability. Significant progress is being made to achieve a world free of MS. About the National Multiple Sclerosis Society The National MS Society, founded in 1946, is the global leader of a growing movement dedicated to creating a world free of MS. The Society funds cutting-edge research for a cure, drives change through advocacy and provides programs and services to help people affected by MS live their best lives. Connect to learn more and get involved: nationalmssociety.org , Facebook , X (formerly known as Twitter), Instagram , YouTube or 1-800-344-4867 .
Cognitive Motor Study