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Please click here to join. Details Rationale: Fatigue is one of the most common and challenging symptoms reported by people with MS. Medication-based treatments have had mixed results in studies, but other research done outside of the US has shown promising results from a “digital therapeutic” program, which guides people in self-management of fatigue An American English version of that program is one of the programs being tested in the CAFE -MS study. This study is being conducted with the goal of gaining U.S. Food and Drug Administration approval to treat fatigue in MS.Eligibility and Details: Participants should be US residents, older than 22, diagnosed with MS, and signed up with the iConquerMS patient registry. They should have moderate or severe fatigue that impacts their daily life, which will be measured using the Fatigue Severity Scale questionnaire.Participants should be fluent in English and have access to the internet and e-mail. Participants should not have had a relapse, started a new disease-modifying therapy, or had steroid treatment in the four weeks before being screened for study eligibility. Other criteria may apply. What is Involved? In all, 2,000 people with MS will be randomly assigned to complete one of two six-month online fatigue management programs, or continue with their usual treatment. Both online programs contain potentially useful information to help people with MS understand and manage their fatigue. Participants assigned to the other digital program or control arm for the first 6 months will have an opportunity to choose to participate in the intervention for the final 6 months of the trial.Participants will fill out questionnaires monthly for six months, and again one year after entering the study. Participants will receive up to $120 for completing these surveys. Primarily, the study is measuring whether the programs reduce physical and mental fatigue. The study also is looking at the effects on other symptoms, everyday activities, and treatment acceptability. Contact: For more information, please visit cafems.iconquerms.org . If you are interested in participating click the “Join the Trial” button, or fill out this webform . Without participants in research studies, MS research would come to a standstill. Participate in MS research . " c-nmssatomrichtext_nmssatomrichtext-host="">Summary Investigators in the United States are recruiting 2,000 people with multiple sclerosis for a study determining whether an online program can reduce fatigue by improving self-management. The study is sponsored by Accelerated Cure and the Department of Defense MS Research Program. This study also is known as the Confirmatory Trial for Alleviating Fatigue in Multiple Sclerosis (CAFE-MS). Important Note: To participate, you must create an iConquerMS account and complete a short interest form. This two-step process takes less than 5 minutes and opens the door to contributing to CAFE-MS and other MS research opportunities. By joining iConquerMS, you become part of a national MS research network led by people living with MS who are helping to shape the future of MS science.Please click here to join. Details Rationale: Fatigue is one of the most common and challenging symptoms reported by people with MS. Medication-based treatments have had mixed results in studies, but other research done outside of the US has shown promising results from a “digital therapeutic” program, which guides people in self-management of fatigue An American English version of that program is one of the programs being tested in the CAFE -MS study. This study is being conducted with the goal of gaining U.S. Food and Drug Administration approval to treat fatigue in MS.Eligibility and Details: Participants should be US residents, older than 22, diagnosed with MS, and signed up with the iConquerMS patient registry. They should have moderate or severe fatigue that impacts their daily life, which will be measured using the Fatigue Severity Scale questionnaire.Participants should be fluent in English and have access to the internet and e-mail. Participants should not have had a relapse, started a new disease-modifying therapy, or had steroid treatment in the four weeks before being screened for study eligibility. Other criteria may apply. What is Involved? In all, 2,000 people with MS will be randomly assigned to complete one of two six-month online fatigue management programs, or continue with their usual treatment. Both online programs contain potentially useful information to help people with MS understand and manage their fatigue. Participants assigned to the other digital program or control arm for the first 6 months will have an opportunity to choose to participate in the intervention for the final 6 months of the trial.Participants will fill out questionnaires monthly for six months, and again one year after entering the study. Participants will receive up to $120 for completing these surveys. Primarily, the study is measuring whether the programs reduce physical and mental fatigue. The study also is looking at the effects on other symptoms, everyday activities, and treatment acceptability. Contact: For more information, please visit cafems.iconquerms.org . If you are interested in participating click the “Join the Trial” button, or fill out this webform . Without participants in research studies, MS research would come to a standstill. Participate in MS research . Please click here to join. Details Rationale: Fatigue is one of the most common and challenging symptoms reported by people with MS. Medication-based treatments have had mixed results in studies, but other research done outside of the US has shown promising results from a “digital therapeutic” program, which guides people in self-management of fatigue An American English version of that program is one of the programs being tested in the CAFE -MS study. This study is being conducted with the goal of gaining U.S. Food and Drug Administration approval to treat fatigue in MS.Eligibility and Details: Participants should be US residents, older than 22, diagnosed with MS, and signed up with the iConquerMS patient registry. They should have moderate or severe fatigue that impacts their daily life, which will be measured using the Fatigue Severity Scale questionnaire.Participants should be fluent in English and have access to the internet and e-mail. Participants should not have had a relapse, started a new disease-modifying therapy, or had steroid treatment in the four weeks before being screened for study eligibility. Other criteria may apply. What is Involved? In all, 2,000 people with MS will be randomly assigned to complete one of two six-month online fatigue management programs, or continue with their usual treatment. Both online programs contain potentially useful information to help people with MS understand and manage their fatigue. Participants assigned to the other digital program or control arm for the first 6 months will have an opportunity to choose to participate in the intervention for the final 6 months of the trial.Participants will fill out questionnaires monthly for six months, and again one year after entering the study. Participants will receive up to $120 for completing these surveys. Primarily, the study is measuring whether the programs reduce physical and mental fatigue. The study also is looking at the effects on other symptoms, everyday activities, and treatment acceptability. Contact: For more information, please visit cafems.iconquerms.org . If you are interested in participating click the “Join the Trial” button, or fill out this webform . Without participants in research studies, MS research would come to a standstill. Participate in MS research . " c-nmssatomrichtext_nmssatomrichtext-host="">Summary Investigators in the United States are recruiting 2,000 people with multiple sclerosis for a study determining whether an online program can reduce fatigue by improving self-management. The study is sponsored by Accelerated Cure and the Department of Defense MS Research Program. This study also is known as the Confirmatory Trial for Alleviating Fatigue in Multiple Sclerosis (CAFE-MS). Important Note: To participate, you must create an iConquerMS account and complete a short interest form. This two-step process takes less than 5 minutes and opens the door to contributing to CAFE-MS and other MS research opportunities. By joining iConquerMS, you become part of a national MS research network led by people living with MS who are helping to shape the future of MS science.Please click here to join. Details Rationale: Fatigue is one of the most common and challenging symptoms reported by people with MS. Medication-based treatments have had mixed results in studies, but other research done outside of the US has shown promising results from a “digital therapeutic” program, which guides people in self-management of fatigue An American English version of that program is one of the programs being tested in the CAFE -MS study. This study is being conducted with the goal of gaining U.S. Food and Drug Administration approval to treat fatigue in MS.Eligibility and Details: Participants should be US residents, older than 22, diagnosed with MS, and signed up with the iConquerMS patient registry. They should have moderate or severe fatigue that impacts their daily life, which will be measured using the Fatigue Severity Scale questionnaire.Participants should be fluent in English and have access to the internet and e-mail. Participants should not have had a relapse, started a new disease-modifying therapy, or had steroid treatment in the four weeks before being screened for study eligibility. Other criteria may apply. What is Involved? In all, 2,000 people with MS will be randomly assigned to complete one of two six-month online fatigue management programs, or continue with their usual treatment. Both online programs contain potentially useful information to help people with MS understand and manage their fatigue. Participants assigned to the other digital program or control arm for the first 6 months will have an opportunity to choose to participate in the intervention for the final 6 months of the trial.Participants will fill out questionnaires monthly for six months, and again one year after entering the study. Participants will receive up to $120 for completing these surveys. Primarily, the study is measuring whether the programs reduce physical and mental fatigue. The study also is looking at the effects on other symptoms, everyday activities, and treatment acceptability. Contact: For more information, please visit cafems.iconquerms.org . If you are interested in participating click the “Join the Trial” button, or fill out this webform . Without participants in research studies, MS research would come to a standstill. Participate in MS research . nationalmssociety.org, Facebook , X (formerly known as Twitter), Instagram , YouTube or 1-800-344-4867 . " c-nmssatomrichtext_nmssatomrichtext-host="">About Multiple Sclerosis Multiple sclerosis is an unpredictable disease of the central nervous system. Currently there is no cure. Symptoms vary from person to person and may include disabling fatigue, mobility challenges, cognitive changes, and vision issues. An estimated 1 million people live with MS in the United States. Early diagnosis and treatment are critical to minimize disability. Significant progress is being made to achieve a world free of MS. About the National Multiple Sclerosis Society The National MS Society, founded in 1946, is the global leader of a growing movement dedicated to creating a world free of MS. The Society funds cutting-edge research for a cure, drives change through advocacy and provides programs and services to help people affected by MS live their best lives. Connect to learn more and get involved: nationalmssociety.org , Facebook , X (formerly known as Twitter), Instagram , YouTube or 1-800-344-4867 . nationalmssociety.org, Facebook , X (formerly known as Twitter), Instagram , YouTube or 1-800-344-4867 . " c-nmssatomrichtext_nmssatomrichtext-host="">About Multiple Sclerosis Multiple sclerosis is an unpredictable disease of the central nervous system. Currently there is no cure. Symptoms vary from person to person and may include disabling fatigue, mobility challenges, cognitive changes, and vision issues. An estimated 1 million people live with MS in the United States. Early diagnosis and treatment are critical to minimize disability. Significant progress is being made to achieve a world free of MS. About the National Multiple Sclerosis Society The National MS Society, founded in 1946, is the global leader of a growing movement dedicated to creating a world free of MS. The Society funds cutting-edge research for a cure, drives change through advocacy and provides programs and services to help people affected by MS live their best lives. Connect to learn more and get involved: nationalmssociety.org , Facebook , X (formerly known as Twitter), Instagram , YouTube or 1-800-344-4867 .
Trial alert online program fatigue